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McDonald's was the restaurant chain with the most U.S. systemwide sales in 2019.

The largest restaurant chains in America ranked by U.S. systemwide sales

NRN’s annual Top 200 report tracks the performance of the country’s largest restaurant chains. The 2020 Top 200 chains, ranked here by Latest-Year U.S. systemwide sales, together make up $313.5 billion in annual domestic sales, up 3.8% from $301.9 billion a year earlier. Individual chains on the list range in size from more than $40 billion to $161 million. 

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